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Confusion in the Elderly After Colon Surgery | Clinical Trials | Clareo Health

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UNKNOWNNCT01623297

Confusion in the Elderly After Colon Surgery

A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.

Lead sponsor: New York Hospital Queens•1 U.S. locations•View source on ClinicalTrials.gov

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Contacts

Mitchell Chorost, MD

CONTACT

718-670-1185 mchorost@nyp.org

Mitchell I Chorost, MD

CONTACT

718-670-1185 mchorost@nyp.org

Sponsors

Lead Sponsor

New York Hospital Queens

Collaborators

New York State Department of Health

Cognitive changes in the elderly are common after surgery. It is not known if minimally invasive or laparoscopic surgery can prevent these changes. A study will be conducted on patients scheduled to have abdominal surgery. The patients will have cognitive evaluations before and after surgery. A small amount of blood, about 2 tablespoons, will be collected no more than 5 times in 6 months. The results will be analyzed to determine if there are changes between those having open surgery versus patients having laparoscopic or minimally invasive surgery, and if these changes coincide with cognitive changes.

Age

65 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Patients over age 65.0 years and in need of elective colon resection for adenocarcinoma

Exclusion Criteria

•Inability to complete preoperative cognitive screening
•Inability to complete study in English since CANTAB is timed and not validated with interpreters
•Emergency surgery
•Depression or psychiatric comorbidity
•Pre-existing dementia
•Previous cerebrovascular accident or "stroke"
•Previous myocardial infarction
•Cardiac ejection fraction below 55%
•Propranolol, metoprolol or other betablocker use
•Digoxin, procainamide, or amiodarone use
•Calcium channel blocker use
•History of vascular surgery or arterial vascular disease
•History of alcohol dependence
•Lovastatin or other HMG-CoA reductase inhibitor use
•Ace inhibitor use
•Neuroendocrine or catecholamine associated tumors
•Hypertension
•Diabetes
•Benzodiazepine use
•Dimenhydrinate or other medications to treat motion sickness
•Metaclopramide use

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 19, 2012Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment52

Start dateJan 2012

Last updatedJun 19, 2012

Condition

Confusion Inflammation Acute Phase Reaction Surgery Delirium

Locations shown

New York Hospital Queens

Flushing, New York

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 19, 2012Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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