Pregnant or breastfeeding females

Systemic anti-melanoma therapy within the 2 weeks prior to the pre-study 18F FDG PET/CT scan until after the 18F MEL050 PET/CT scan

Patients whose clinical care may be compromised because of the delay resulting from performance of the 18F MEL050 PET/CT scan

Patients whose only metastatic lesion is in the Central Nervous System

Patients with urinary incontinence or patients who cannot comfortably hold their urine for more than 90 minutes

Any serious medical condition which the investigator feels may interfere with the procedures or evaluations of the study

Patients unwilling or unable to comply with protocol and patients with a history of non compliance or inability to grant informed consent.

Of 18F MEL050 Using PET/CT in Metastatic Melanoma