Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Spaulding Rehabilitation Hospital
With
National Institute of Neurological Disorders and Stroke (NINDS)
Highland Instruments, Inc.
Age
40–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Documentation of PD diagnosis from their clinician by either a letter or verification through their medical record
Research criteria of "possible" or "probable" PD, as defined by Gelb et al (Gelb D, Oliver E, Gilman S. Diagnostic Criteria for Parkinson Disease. Arch Neurol.1999;56:33-39)\[1\]
Age 40 or over;
Taking stable medications for at least 30 days
You may not be if
Features suggestive of other causes of parkinsonism/Parkinson's-plus syndromes;
History of deep brain stimulation or ablation surgery, mass brain lesions;
History of schizophrenia, schizoaffective disorder, other psychosis, episode of bipolar illness, alcohol/drug abuse within the past year;
Need for rapid clinical response due to conditions such as initiation, psychosis, or suicidal;
Contraindications to transcranial brain stimulation or TUS, i.e. metal in the head, implanted brain medical devices, etc;
Unstable medical conditions (e.g. uncontrolled diabetes, uncompensated cardiac issues, heart failure, pulmonary issues, or chronic obstructive pulmonary disease);
Pregnancy.
Epilepsy or disorders that increase likelihood of seizures including: moderate or severe traumatic brain injury, congenital birth defects leading to seizures, brain tumor, metabolism disorders associated with seizures, and nonlacunar stroke.
