Exercise as a Behavioral Treatment for Cocaine Dependence

Exclusion Criteria

• •Potential participants will be excluded if any of the following apply:
• •1\. Have neurological or psychiatric disorders, as assessed by MINI, such as: a. current major depression; b. lifetime history of schizophrenia, other psychotic illness, or bipolar illness; c. current organic brain disease or dementia assessed by clinical interview; d. current psychiatric disorder as assessed by the MINI including history of suicide attempts within the past three months and/or current suicidal ideation/plan
• •2\. Meet DSM-IV criteria for abuse or dependence on other drugs, except for cocaine or nicotine
• •3\. Have any of the conditions defined by the American College of Sports Medicine (2006) as "absolute contraindications to exercise testing"
• •4\. Have evidence of clinically significant heart disease or hypertension
• •5\. Have evidence of clinically significant or unstable medical illness including: neuroendocrine, autoimmune, renal, hepatic, or active infectious disease
• •6\. Be pregnant or nursing. All females must provide a negative pregnancy urine test
• •7\. Currently use alpha or beta agonists, theophylline, or other sympathomimetics
• •8\. Currently engaged in an exercise regimen of similar intensity as those planned for investigation
• •9\. Have any other illness, condition, or use of medications, which in the opinion of the PI and/or the study physician would preclude safe and/or successful completion of study.