Evaluation of Drug-drug Interaction Between LCZ696 and Sildenafil in Subjects With Mild to Moderate Hypertension

Inclusion Criteria

• •Male subjects with mild to moderate hypertension, either treated or not currently on treatment, between age 18 and 65 years of age, and otherwise in good health as determined by past medical history, physical examination, vital signs, electrocardiogram, and laboratory tests at screening.
• •At screening: systolic blood pressure 120-140 mmHg on therapy, or 140-160 mmHg if untreated
• •At screening: diastolic blood pressure, 70-95 mmHg on therapy, or 90-100 mmHg if untreated
• •Baseline: BP ≥140/90;