Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Age
50–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients older than 50 years
meeting criteria for a diagnosis of major depressive disorder (DSM IV code 296.2x or 296.3x) as confirmed by a score \> 20 on the HAM-D 24 items scale and a structured clinical interview using the SCID by a consultant psychiatrist
You may not be if
Treatment resistant depression (as defined by failure to respond to ≥2 adequate antidepressant trials)
Major depressive disorder with psychosis (296.x4)
Those with depression who fulfill the chronic specifier (MDE for \>2 years)
Significant Axis II pathology
Previous trial with mirtazapine
Concurrent antipsychotic usage
Comorbid dementia (as confirmed by MMSE \< 24)
Substance misuse including drug and/or alcohol dependence/abuse in the past 3 months
Bipolar disorder
Schizophrenia
Obsessive compulsive disorder
Post traumatic stress disorder
Eating disorder
Head injury
Recent stroke (\< 3 months)
Recent MI (\< 3 months)
Currently actively participating in structured/formal psychotherapy
Being non ambulatory
Those actively suicidal
Those incapable of informed consent
Clareo Health | LEPR Polymorphism Weight Gain by Mirtazapine in Late Life Depression
