CURE Addiction Center of Excellence: Brain Mechanisms of Relapse and Recovery

Exclusion Criteria

• •1. Current severe alcohol dependence that requires medical supervision for alcohol withdrawal;
• •2. Current psychosis, dementia, mental retardation, or history of schizophrenia;
• •3. Significant clinical abnormalities in hematology, chemistry, or urinalysis;
• •4. Significant clinical cardiovascular, neurological, hepatic, renal, pulmonary, metabolic, endocrine, or gastrointestinal disorders;
• •5. Female subjects who are pregnant or lactating, or female subjects of childbearing potential who are not using birth control (oral contraceptives, barrier (diaphragm or condom) plus spermicide, or levonorgestrel implant); (Pregnancy testing will be done on all females of child bearing age); and
• •6. Current diagnosis of chronic pain disorder.