Chemotherapy-Induced Cognitive Impairment

Inclusion Criteria

• •* Participants must be females between 35 and 70 years of age.
• •* Participants must have been diagnosed with breast cancer and completed chemotherapy,within the preceding 2 years.
• •* Participants must have completed their intended full course of chemotherapy regimen at least 30 days prior to participation.
• •* Participants must have been diagnosed with invasive ductal or lobular BrCa Stages I, II, or III (American Joint Committee on Cancer (AJCC) staging manual, 7th edition, 2010).
• •Participants must be able to read, write, and speak English fluently.
• •Participants must be able to provide a valid informed consent.
• •Participants must have a life expectancy of greater than 6 months at the time they are approached for enrollment.
• •Cases - Those who self-report CICI and are in the 75th percentile of scores on the Cognitive Failures Questionnaire (CFQ) and have a global rating of cognition response of "Extremely Affected" or "Strongly Affected"
• •Controls - Those whose CFQ scores are in the lowest 25th percentile and who report that their daily life is not affected by cognitive impairment. Controls will be selected so that they are age (within 5 years)-matched to a Case.