History of Pure Red Cell Aplasia (PRCA) or anti-erythropoietin (EPO) antibodies

Contraindications for ESA therapy

Serum albumin \< 3.0 g/dL

Immunocompromized patients (immunosuppressive treatment, chemotherapy)

Hepatitis C infection on an active treatment or hepatitis B or human immunodeficiency virus (HIV) infection

Systemic lupus erythematosus

Symptomatic congestive heart failure, Unstable angina pectoris, or myocardial infarction within 6 months

History of malignancy of any organ system within the last 5 years

History of use of any non-EU approved ESA

HX575 Epoetin Alfa Subcutaneously (s.c.) in Chronic Kidney Disease (CKD)