Pilot Study of 99mTc-MIP-1404 SPECT/CT Imaging in Men With Prostate Cancer Undergoing Prostatectomy and/or Pelvic Lymph Node Dissection

Inclusion Criteria

• •1. Male aged 21 years or older.
• •2. Ability to provide signed informed consent and willingness to comply with protocol requirements.
• •3. Past biopsy indicating the presence of adenocarcinoma of the prostate gland.
• •4. Participant is deemed to be high-risk with potential for pelvic lymph node involvement. The criteria for high-risk are:
• •* Patient has PSA value \>10 and clinical stage T2 or higher, and Gleason score 8, 9 or 10.
• •* Patient has PSA value \>20 and clinical stage T2 or higher, and Gleason score
• •5. Participant is or will be scheduled to undergo standard of care prostatectomy and/or pelvic lymph node dissection.
• •6. Have had (within previous 2 months) or will undergo diagnostic CT or MRI imaging prior to surgery.
• •7. Have had (within previous 2 months) or will undergo bone scan imaging prior to surgery.
• •8. Participants must agree to use an acceptable form of birth control throughout the study period. Participants must use condoms for a period of seven days after each injection, if engaged in sexual activity.