Distress Tolerance and Buprenorphine

Exclusion Criteria

• •current methadone maintenance treatment program participation
• •medically necessary prescription opioid treatment (e.g., for chronic pain)
• •current criteria for a DSM-IV diagnosis of substance dependence for sedative/hypnotic drugs, alcohol, stimulants, cocaine, inhalants, hallucinogens
• •a diagnosis of organic brain disorder, bipolar disorder, schizophrenia, schizo-affective, schizophreniform, or paranoid disorder, or major depression (subjects who meet criteria for "substance-induced mood disorder," or dysthymia only will not be excluded)
• •current suicidality on the Modified Scale for Suicidal Ideation
• •use of daily psychotropic, antidepressant, or anxiolytic medication
• •evidence of neuropsychological dysfunction as assessed by the study physician with confirmation with the Folstein Mini-Mental Status Examination
• •anticipated major painful event (significant surgical procedure) in the coming 6 months
• •probation/parole requirements that might interfere with protocol participation
• •history of allergic reaction to buprenorphine or naloxone.