The Influence of Pressure Pain on [11C]Diprenorphine Binding Potentials

Exclusion Criteria

• •Current significant medical, neurological, or psychiatric illness as assessed by the Physician Investigators
• •Women who are pregnant or breast feeding, have gone through menopause, and/or have irregular menstrual cycles
• •Claustrophobia
• •History of head trauma
• •Instability of responses to experimental pain (See Study Procedure Section Part II)
• •History of asthma
• •Use of psychotropic drugs or hormone treatments (including hormonal birth control) within one year of date of consent
• •History of smoking
• •Routine exercise in excess of one hour per day and/or three times per week
• •Non-fluent English speaker