Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients

Exclusion Criteria

• •1. Hepatitis C Virus (HCV) infection of mixed genotype; Hepatitis B Virus (HBV) or Human Immunodeficiency Virus (HIV) co-infection
• •2. Evidence of acute or chronic liver disease due to causes other than chronic HCV infection,
• •3. Decompensated liver disease, or history of decompensated liver disease,
• •4. Body weight \< 40 or \> 125 kg,
• •5. Clinical evidence of significant or unstable cardiovascular disease, chronic pulmonary disease, history or evidence of retinopathy or clinically significant ophthalmological disorder
• •6. Pre-existing psychiatric condition that could interfere with the subject's participation in and completion of the study
• •7. Laboratory parameters disorders (thalassemia major, sickle cell anemia or glucose 6 phosphate dehydrogenase deficit)
• •8. Hemoglobin \< 12 g/dL for women and \< 13 g/dL for men
• •9. Patients who have been previously treated with at least one dose of any antiviral or immunomodulatory drug other than interferon alfa or ribavirin for acute or chronic HCV infection