Pharmacokinetics of Biphasic Insulin Aspart 30 and 70 in Subjects With Type 1 Diabetes

Exclusion Criteria

• •Treatment with insulin aspart within the last 14 days prior to this trial
• •The receipt of any investigational drug within the last 30 days prior to this trial
• •Total daily insulin dose at least 1.8 U/kg
• •A history of drug abuse or alcohol dependence within the last 5 years
• •Impaired hepatic function
• •Impaired renal function
• •Blood donation within the last nine weeks or haemoglobin below the lower reference limit according to the local laboratory
• •Cardiac disease
• •Severe, uncontrolled hypertension