Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre for Addiction and Mental Health
With
Canadian Institutes of Health Research (CIHR)
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
1. Have a Full Scale IQ ≥ 80 as determined by the Shipley-2 which provides an estimate of pre-morbid intelligence
2. Be non-treatment seeking smokers;
3. Have a score greater than 5 on the Fagerstrom Test of Nicotine Dependence (FTND), a 5-item multiple choice questionnaire which assesses nicotine dependence
4. Report smoking of at least 10 cigarettes per day using a self-report 7-day timeline follow-back
5. Have an expired breath CO level \>10ppm
6. Be able to provide informed consent.
1. Meet SCID for DSM-IV diagnostic criteria for schizophrenia or schizoaffective disorder
2. Be in stable remission from positive symptoms of psychosis as judged by psychiatric evaluation and a PANSS total score \<70
3. Be receiving a stable dose of antipsychotic mediation(s) for at least one month.
1. Do not meet SCID for DSM-IV criteria for any current or past psychiatric disorder except for past major depression if it has been in remission for a minimum of one year
2. Not taking any psychotropic medications
You may not be if
1. Meet criteria for abuse or dependence of alcohol or illicit substances within the past 3 months (with the exception of nicotine dependence or caffeine)
2. Use of nicotine replacement or tobacco products other than cigarettes
3. Concomitant medical illness (including unstable or other presentations thought by investigators to compromise study participation, e.g. diabetes mellitus, hypothyroidism or acute/chronic renal insufficiency) or neurological illness including a history of seizures or a first-degree relative with a history of a seizure disorder
