There are over 500 types of bacteria in the mouth. Most of these bacteria do not cause disease. However, some mouth bacteria can cause tooth decay and gum disease. The purpose of a probiotic tablet for the mouth is to put known healthy bacteria in the mouth. This study will compare the effect of the probiotic tablet on the levels of harmful or disease causing bacteria in the mouth to a placebo tablet that does not contain any probiotic bacteria.
Age
18–35
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
minimum of 20 teeth, with only a few fillings
good general health
willing to use an appropriate method of birth control during the study
measurable levels of Streptococcus mutans and one or more of the selected periodontal pathogens
You may not be if
chronic or acute illness such as heart disease, diabetes, cancer, hepatitis (liver disease) or HIV positive
radiation therapy or systemic cancer treatment (chemotherapy)
require antibiotics for dental treatment
pregnant or planning to become pregnant during the study period
Clareo Health | Effect of an Oral Probiotic Tablet on Oral Bacteria and Clinical Measurements (ProBiora3)