Comparison of Closed-loop Operation After Morning Meal With and Without Carbohydrate Counting

Exclusion Criteria

• •Clinically significant nephropathy, neuropathy (especially clinically significant gastroparesis) or retinopathy as judged by the investigator.
• •Recent (\< 3 months) acute macrovascular event e.g. acute coronary syndrome or cardiac surgery.
• •Pregnancy.
• •Severe hypoglycemic episode within two weeks of screening.
• •• Medication likely to affect with the interpretation of the results: Prandase, Victoza, Byetta and Symlin
• •Known or suspected allergy to the trial products or meal contents.
• •Other serious medical illness likely to interfere with study participation or with the ability to complete the trial by the judgment of the investigator.
• •Failure to comply with team's recommendations (e.g. not willing to eat snack, not willing to change pump parameters, etc).
• •Unreliable carbohydrate counting
• •Problems with venous access