Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vertex Pharmaceuticals Incorporated
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Healthy subjects (male and female of non-childbearing potential) between the ages of 18 and 55 years
Non-childbearing potential female subjects
Male subjects and female partners must agree to use at least 2 methods of contraception
Subjects with a body mass index (BMI) of 18 to 30 kg/m2 and weigh \>50 kg at the Screening Visit.
You may not be if
Subjects with a positive test result for hepatitis B, hepatitis C, or HIV
Subjects with a significant history of any illness, as deemed important by the investigator or any condition possibly affecting drug absorption
Subjects with a positive urine screen for drugs of abuse
Subjects with a history of regular alcohol consumption
Subjects treated with an investigational drug within 30 days
For Part A only: Subjects with 12-lead ECG QTcF \>450 msec (males) or QTcF \>470 msec (females) at the Screening Visit
Subjects who use prescription and/or nonprescription medications or vitamins and/or dietary supplements
Subjects who have made a blood donation of approximately 1 pint (500 mL) within 56 days prior to the first dose of study drug
Subjects who have a female partner who is pregnant, nursing, or planning to become pregnant during the study or within 90 days of the last dose of study drug
Subjects on hormone replacement therapy (HRT) must discontinue such therapy 28 days prior to the first dose of study drug
Subjects who have a habit of using tobacco or nicotine containing products within 6 months before the Screening Visit
