Comparison of Liraglutide Inhaled Into the Lungs Compared to Liraglutide Injected Under the Skin in Healthy Male Volunteers

Exclusion Criteria

• •A clinically significant illness or infection requiring treatment within the last two months
• •Any infection involving the respiratory system or adverse event that may, in the opinion of the principal investigator, interfere with blood glucose homeostasis
• •Subjects with first and/or second degree relative(s) with diabetes mellitus
• •Donation or loss of greater than 500 ml of blood in the period 0-12 weeks before trial entry
• •Alcohol use in excess of 28 units of alcohol per week. A unit of alcohol is equivalent to half a pint of average strength beer, a glass (125 ml) of wine or a pub measure (25 ml) of spirits, sherry or port
• •Current addiction to alcohol or substances of abuse
• •Females
• •Presence of hepatitis B surface antigen, hepatitis C antibody or HIV (human immunodeficiency virus) 1 or 2 antibodies