Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Colorado, Denver
With
University of Illinois at Chicago
University of Pittsburgh
Rush University Medical Center
National Institute of Neurological Disorders and Stroke (NINDS)
Northwestern University
The overall objective of this study is to determine the futility or non-futility of conducting a randomized controlled trial to determine the effects of exercise on the progression of PD symptoms. The primary aim is to determine whether individuals with de novo Parkinson's disease (naïve to drug treatment) can achieve the randomly assigned levels of mean exercise intensity (60-65% HRmax or 80-85% HRmax) and adhere to the exercise protocol.
Age
40–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Clinical diagnosis of primary Parkinson's disease
In a Hoehn and Yahr stage less than stage III
Disease duration is less than 5 years
Not likely to require dopaminergic therapy within 6 months
You may not be if
Use of any PD medication within 60 days prior to the beginning the study, including levodopa, direct dopamine agonists, amantadine, Rasagiline (Azilect), Selegiline (Eldepryl), Artane (trihexyphenidyl).
Duration of previous use of medications for PD that exceeds 90 days
Expected to require dopaminergic therapy in the next 6 months
Poorly controlled or unstable cardiovascular disease
Uncontrolled hypertension
Hypo- or hyperthyroidism, abnormal liver function, abnormal renal function
Depression that precludes ability to exercise (Beck depression score\>13)
Disorders that interfere with ability to perform endurance exercises
Regular participation in vigorous endurance exercise
Evidence of serious arrhythmias or ischemic heart disease
Any clinically significant medical condition, psychiatric condition, drug or alcohol abuse, or laboratory abnormality that would, in the judgment of the investigators, interfere with the ability to participate in the study
Clareo Health | Study in Parkinson's Disease of Exercise
