Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Avid Radiopharmaceuticals
Age
50–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Male or female \> 50 years of age
Meet the diagnostic criteria for probable DLB as established by the DLB Consortium (McKeith et al., 2005)
Male or female \> 50 years of age
Meet the NINCDS criteria for probable AD and have a Mini Mental State Examination (MMSE) score at screening between 10 and 24 inclusive
Male or female \> 50 years of age
Have probable PD according to the following criteria (Gelb et al., 1999):
* Presence of 2 of the following 3 features: rest tremor, rigidity, bradykinesia;
* Documented history of a sustained (\>6 months) improvement to Levodopa (L-DOPA) or a dopamine agonist
* Absence of atypical clinical features or other possible signs or symptoms suggesting another cause of parkinsonism such as a history of frequent falls as a prominent early feature, localized brain lesion(s) or neuroleptic use
* Asymmetric onset
A diagnosis of PD made within the 4 years prior to enrollment
Normal subjects:
Are males or females \> 50 years of age
Have a MMSE score \> 29, and are cognitively normal on the psychometric test battery at screening
Have no signs or symptoms of clinically meaningful parkinsonism
You may not be if
Have a history or current diagnosis of other neurologic disease
Have evidence of clinically significant cerebrovascular disease
Have evidence from MRI or other biomarker studies that suggests the presence of a CNS pathology other than that associated with the study diseases
