Neoadjuvant Chemotherapy for Operable Premenopausal Breast Cancer Patients

Exclusion Criteria

• •1. The patients have other cancers at the same time or have the history of other cancers in recent five years, excluding the controlled skin basal cell carcinoma or skin squamous cell carcinoma or carcinoma in situ of cervix.
• •2. The patients have active infections that were not suitable for chemotherapy.
• •3. The patients have severe non-cancerous diseases.
• •4. The patients are undergoing current administration of anti-cancer therapies, or are attending some other clinical trails.
• •5. The patients whose breast cancers are HER2 positive and choose to undergo the neoadjuvant chemotherapy that includes herceptin regimen.
• •6. The patients are pregnant or lactational, or they refuse to practice contraception during the whole trial.
• •7. The patients are in some special conditions that they can't understand the written informed consent, such as they are demented or hawkish.
• •8. The patients have allergic history of the chemotherapeutic agents.
• •9. The patients have bilateral breast cancers.