Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients

Exclusion Criteria

• •1. Patients with loss of consciousness or confused
• •2. Patients with cardiogenic shock
• •3. Patients with the left circumflex or the right coronary artery (RCA) as the culprit artery, or with evidence of coronary collaterals to the risk region
• •4. Patients with an opened (TIMI \> 1) LAD coronary artery at admission on initial (admission) coronary angiography
• •5. Patients with 5.2. known hypersensitivity to cyclosporine 5.3. known hypersensitivity to egg, peanut or Soya-bean proteins 5.4. known renal insufficiency (either known creatinin clearance \< 30 ml/min/1.73m² or current medical care for severe renal insufficiency) 5.5. known liver insufficiency 5.6. uncontrolled (treated or untreated) hypertension (\> 180/110 mmHg)
• •6. Patients treated with any compound containing Hypericum perforatum (St.-John's-worth) or Stiripentol or Aliskiren or Bosentan or Rosuvastatine
• •7. Female patients currently pregnant or women of childbearing age who were not using contraception (oral diagnosis).
• •8. Patients with any disorder associated with immunological dysfunction more recently than 6 months prior to presentation 8.2. cancer, lymphoma 8.3. known positive serology for HIV, or hepatitis