Pharmacokinetics of Somatropin in Patients With End Stage Renal Disease Receiving Chronic Haemodialysis

Inclusion Criteria

• •PATIENTS:
• •Male or female, age equal to or above 18 years undergoing chronic haemodialysis
• •Stable and adequate haemodialysis treatment three months prior to enrolment
• •HEALTHY SUBJECTS:
• •Matching an individual of the patient group by: Gender and age (± 5 years)
• •Matching an individual of the patient group by weight (after dialysis, ±10%)
• •Creatinine clearance above 80 ml/min
• •Subjects must be in good health in accordance with their age as determined by a medical
• •history, physical examination, vital signs, ECG (electrocardiogram), routine haematology and clinical chemistry