ASA \> III

inability to provide informed consent

Bleeding disorders

Contraindications to nonsteroidal anti-inflammatory drugs (NSAIDs)

Allergy to amide-type local anesthetics or NSAIDs

Infection at the thoracic paravertebral injection site

Pregnancy or breast-feeding

Severe spine or chest wall deformity

body mass index equal to or more than 24 kg/m2

patients with major psychosis or drug and alcohol abuse

patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease

Patients with significant visual impairment or other physical disability that precludes complete cooperation

Quality Study of Anesthetic Technique on Breast Cancer Surgery