RGD-PET-CT in Cancer Angiogenesis

Inclusion Criteria

• •1. Patients should have advanced or metastatic RCC confirmed by histological diagnosis
• •2. Patients considered suitable for therapy with TKI for RCC according to responsible clinician
• •3. Measurable tumour according to RECIST v1.1 criteria
• •4. Standard staging CT scan performed within 28 days of first research scan
• •5. The patient has not received chemotherapy, radiotherapy, surgery or any other treatment against cancer within 4 weeks prior to recruitment
• •6. Age ≥18 years
• •7. Adequate renal function (creatinine \<1.25xULN)
• •8. Patient is able to tolerate and comply with scanning procedure
• •9. Patient is not lactating or pregnant
• •10. Absence of any psychological, familial, sociological or geographical condition which in the opinion of the Investigator may potentially hamper compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial
• •11. Able and willing to give informed consent