Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye

Inclusion Criteria

• •Males or females, of legal age of consent
• •Patient with Stevens-Johnson syndrome in chronic stage or has symptoms more than 3 months and has dry eye symptoms
• •Dry eye symptoms are defined as
• •1. has dry eye symptom everyday for more than 3 months
• •2. has foreign body sensation frequently
• •3. use tear substitutes more than 3 times per day
• •Tear test shaw abnormalities at least 1 of 2 of following:
• •1. Schirmer test without anesthesia is not more than 5 millimeters in 5 minutes
• •2. Fluorescein clearance test at first 10 minutes is not more than 3 millimeters and has at least 1 of 3 of the following:
• •2.1.Rose Bengal score is not less than 4 2.2.Fluorescein stain at cornea 2.3.Impression cytology is consistent to dry eye
• •Patent punctum