Lead Sponsor

University of Vermont

Collaborators

Age

40 - 65 years

Sex

FEMALE

Healthy Volunteers

No

•Post-menopausal (last period 12 mos prior to study enrollment or oophorectomy)
•Age 40-65
•DCIS, Stage I, II, III Breast Cancer
•BMI between 27-50
•Completed chemotherapy to treat early stage breast cancer (Stage I-III) no less then 6 months and no more than 48 months from start of study or for specific aim 3 Diagnosis of DCIS or Stage I breast cancer who did not receive chemotherapy.

•Participant can not have a psychotic or central nervous system impairment that would limit compliance with study requirements
•Evidence of metastatic disease
•Chemotherapy for cancer other than breast cancer
•Diabetes mellitus, uncontrolled hypo or hyper thyroidism, liver failure
•Celiac sprue, inflammatory bowel disease
•Inability to walk for exercise
•Lymphedema as indicated by a 2 cm circumference difference at the elbow
•weight loss in the previous 6 months of 10 lbs or greater

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