Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Samsung Medical Center
With
Guerbet
Study cohort will undergo PET/CT and MRI scans prior to chemotherapy and after the first chemotherapy cycle. MRI scans include DCE-MRI and DWI. The following parameters will be calculated using these values:
1. Metabolic parameters on FDG-PET A. SUV change ratio (SCR) = SUVpost/SUVpre B. MTV change ratio (VCR) = MTVpost/pre C. TLG change ratio = SCR X VCR
2. Perfusion parameters on DCE-MRI A. Kep B. K-trans C. ve
3. Diffusion parameters on DWI A. Mean ADC B. fDM
Age
20–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Histologically proven NSCLC
Newly diagnosed Stage stage IV
Participant is being considered for the chemotherapy with EGFR TKI as a first line therapy
At least one measurable primary or other intrathoracic lesion \>= 2cm, according to RECIST
Performance status of 0 to 2 on the ECOG scale
Age 18 years or older
Able to tolerable PET/CT and MRI imaging required by protocol
Able to give study-specific informed consent
You may not be if
Pure bronchioloalveolar cell carcinoma histology
Thoracic radiotherapy, lung surgery or chemotherapy within three months prior to inclusion in the study
Poorly controlled diabetes
Prior malignancy
Clareo Health | Predictive Value of FDG PET/CT, DWI and DCE-MRI Scans for Non-small Cell Lung Cancer Patients Receiving Chemotherapy
