Undergoing open, elective intracranial procedure for
* tumor resection
* aneurysm clipping
* revascularization
Have an ASA (American Society of Anesthesiologists) physical status of 1, 2, 3, or 4
Able to provide written informed consent
You may not be if
Significant medical disease, laboratory abnormality, or condition that, in the opinion of the investigator, would compromise patient welfare or would otherwise contraindicate study participation
Unable to communicate symptoms
Current daily opioid use (\>40 mg morphine equivalent)
Tramadol use
Treated with MAO (monoamine oxidase inhibitors) inhibitors within 10 days of surgery
Treated with any amount of acetaminophen within 8 hours of anesthesia for surgery
Allergic or hypersensitive to acetaminophen or any contraindications per manufacturer's guidelines
Pregnancy
Impaired liver function
Participation in interventional clinical study within the last 30 days
Known or suspected history of alcohol or drug abuse
Surgery for resection of acoustic neuroma
Transphenoidal tumor resection
Clareo Health | Intravenous Acetaminophen for Craniotomy Patients