Subject with bilateral degenerative disease of hips who are candidate for one-stage bilateral THA
Subject willing and able to provide written informed consent
You may not be if
Subject with significant comorbidities identified by Charleston index of ≥ 3
Subject with malignancy
Subject with history of heart disease, myocardial infarction, pulmonary insufficiency, pulmonary embolus, documented fat emboli syndrome, adult respiratory distress syndrome, documented patent ductus arteriosus or septal defect, chronic renal failure and/or acute hepatic failure or chirhosis
Subjects with hematologic disorders such as anemia (Hb \< 10 g/dL) and sickle cell disease, acquired or congenital coagulopathies, acquired or congenital bleeding disorders,
Subject who received anticoagulant such as aspirin or Warfarin (Coumadin) or antiplatelet agents such as clopidogrel (Plavix) within 7 days of surgery
Subject who received hemostatic agents such as tranexamic acid and aprotinin