Placebo and Active Controlled, Double Dummy Study to Compare Efficacy of Aspirin and Ibuprofen in Treatment of Episodic Tension-type Headache

Exclusion Criteria

• •Other headaches, including migraine, that required medical treatment
• •Hypersensitivity to acetylsalicylic acid, salicylates, ibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs)
• •Serious physical illness especially uncontrolled disorders of kidney, liver, lung, heart or brain function, neurological disorders or severe chronic or terminal disease
• •Mental illness, including depression
• •Needed or were using or likely to need or use any of the prohibited concomitant medications: antidepressants, oxicams
• •Pregnant or lactating women, or sexually active women of child-bearing potential unless using effective contraception
• •Participating in any other clinical study or had done within the previous 4 weeks
• •Had been previously enrolled in this study