Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol

Exclusion Criteria

• •1. Patients with an acute gout flare within 2 weeks prior to the first visit
• •2. Patients with chronic, active gout with at least 1 continuously inflamed joint for at least 4 weeks
• •3. Patients with more than three joints affected by gout
• •4. History of intolerance or allergy to colchicine or allopurinol
• •5. Use of allopurinol, benzbromarone, febuxostat, probenecid, or sulfinpyrazone less than 3 months prior to entering the study
• •6. Use of colchicine less than 14 days prior to entering the study