Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
St Vincent's Hospital, Sydney
With
Merck Sharp & Dohme LLC
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
HIV positive
On HAART, with plasma HIV viral load \< 50 copies/ml for previous 12 months or more
Able to provide informed consent
HAND diagnosis, with symptom progression within previous 6 months (while on existing HAART regimen)
You may not be if
Non-HIV related neurological disorders and active CNS opportunistic infection (as assessed by full blood count, electrolytes, creatinine, glucose, LFT's, cryptococcal antigen, VDRL, MRI brain scan and CSF fluid analysis for cell count, protein, glucose, culture, VDRL and cryptococcal antigen)
Psychiatric disorders on the psychotic axis
Current major depression
Current substance use disorder, or severe substance use disorders within 12 months of study entry
Active HCV (detectable HCV RNA)
History of loss of consciousness \> 1 hour
Non-proficient in English
Medications known to pharmacologically interact with ARV's
Currently taking an Integrase Inhibitor
Pregnancy (as assessed by the urine pregnancy test)
