Extension Study of H01_04TP to Evaluate the Booster Response Induced by Vi-CRM197 in Adults

Inclusion Criteria

• •All Subjects:
• •1. Males and females of age ≥18 to ≤42 years.
• •2. Individuals, who, after the nature of the study have been explained to them, have given written consent according to local regulatory requirements.
• •3. Individuals in good health as determined by the outcome of medical history, physical examination and clinical judgment of the investigator.
• •4. If women, use of birth control one month before study start, a negative pregnancy test and willingness to use birth control measures for the entire study duration.
• •H01\_04TP subjects only:
• •5. Individuals who previously participated in the H01\_04TP study and were vaccinated with either NVGH Vi-CRM197 (5μg) or with the licensed Vi-PS.
• •6. Individuals who have received no Vi vaccination subsequent to the one received in the H01\_04TP study.
• •All subjects:
• •1. Individuals with behavioral or cognitive impairment or psychiatric disease that, in the opinion of the investigator, may interfere with the subject's ability to participate in the study.
• +22 more criteria