Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers

Exclusion Criteria

• •Pregnant or breastfeeding females or those with a positive pregnancy test or who will not use a medically acceptable contraceptive method from selection and during the study.
• •Current relevant disease.
• •Previous chronic processes or with rebound characteristics that could interfere with study according investigator's judgment.
• •Volunteers who have received pharmacological treatment, including medicinal plants, during the four weeks previous to beginning the study.
• •Having used corticoids sporadically in the last 30 days whichever the route aof administration, or any med by ocular or nasal administration route.
• •Case history of hypersensitivity to meds or any other allergic process.
• •Visual alterations: previous eye surgery, glaucoma, use of lenses, uveitis or ocular surface pathology (dry eye, blepharitis).
• •Volunteers with visual alteration with more than 3 dioptres in either eye.
• •Volunteers who has participated in a clinical trial during the past fout months before study entry.
• •Blood or derivate transfusion during the six previous months to study entry.
• •Case history of drug or alcohol abuse or dependence.
• •Positive result in test drug abuse during selection period.
• •positive serology results to hepatitis B virus(HbsAg), virus C o VIH.
• •Analytic alterations medically relevant, at investigator's judgement.