Perfluorocarbon (PFC) Inhalation Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome

Exclusion Criteria

• •Age: \< 18 years old or \> 75 years old
• •During the early stage of the treatment, the use of mechanical ventilation for more than 3 days other than ALI/ARDS for reasons
• •Lung parenchyma and airway surgery carried out within 30 days of the screening period
• •Severe arrhythmia and myocardial ischemia after cardiopulmonary resuscitation
• •Systolic blood pressure \< 90 mm Hg, and can not maintain its stability with intravenous infusion and vasopressor drugs
• •Intubation due to interstitial lung disease (E.g., sarcoidosis, idiopathic pulmonary fibrosis)
• •Any active pneumothorax or mediastinal emphysema
• •Risk factors leading to the death within 3 months in addition to ALI/ARDS during the screening period (E.g., end-stage cancer)
• •Of perfluorocarbons' allergies
• •Pregnant, breastfeeding women
• •Attending other clinical trial within 30 days of the screening period
• •Severe organ dysfunction (Marshall score ≥ 3 or Sequential Organ Failure Assessment（SOFA） score≥ 3, including serious liver and kidney dysfunction, upper gastrointestinal hemorrhage, etc.)
• •Acute Physiology and Chronic Health Evaluation（APACHE） II score ≥ 30, high risk of death
• •The researchers consider other situations not suitable for the case to participate in the study