Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Parisa Gazerani
With
The Ministry of Science, Technology and Innovation, Denmark
Migraine Research Foundation
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Men and women aged between 18 to 65 years Migraine with or without aura, as diagnosed according to the second edition International Classification of Headache Disorders (ICHD-II) Onset of migraine before 50 years of age Headache on 15 or more days per month Migraine-like headache on 8 or more days per month, as per the IHS guidelines
You may not be if
Change in type or dose of migraine prophylactic medication in last 3 months
Medication overuse headache as diagnosed according to the ICHD-IIR
Post-traumatic headache as diagnosed according to the ICHD-II
Other dominant chronic pain condition
Known active inflammatory diseases such as rheumatoid arthritis
History of recent cerebrovascular disorder
Unable to provide written informed consent
Unable to read and write in English
Severe psychological/psychiatric disorders
Recent history of significant trauma, as determined by the Principal Investigator including major surgery within the previous 2 months or major surgery planned during the treatment period
Recent history of drug or alcohol abuse
Any clinically significant findings on screening blood sample results
Current malignancy
Known hypersensitivity to ibudilast or excipients in Ketas® formulation
Renal or hepatic impairment, defined as baseline GFR (as calculated by the Cockcroft-Gault equation) of \<60 mL/min, LFTs (excluding bilirubin) \> 3 times the upper limit of normal or bilirubin \> 2 times the upper limit of normal
For females of childbearing potential:
* Pregnancy
* Lack of adequate contraception (abstinence, double barrier method, intrauterine device, surgical sterilization (self or partner), hormonal contraceptive methods (oral, injected, or implanted)
* Breastfeeding
Clareo Health | Ibudilast in the Treatment of Patients With Chronic Migraine.
