About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDNANCT01382446

Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma

Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and ...

Lead sponsor: St. Joseph's Hospital and Medical Center, Phoenix•1 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

St. Joseph's Hospital and Medical Center, Phoenix

Collaborators

3M

To see a significant decrease in the bacterial load in the oral mucosa and subsequently, a decrease in the pathogenesis of Ventilator Associated Pneumonia through the use of an oral rinse containing 0.12% Chlorhexidine Gluconate as part of an oral care protocol. Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Adults admitted to ICUs located in Tower Two Critical Care Units: Medical, Surgical, Medical #2, and Trauma Intensive Care Units.
•Patients will be randomized to either treatment or standard group based on day of admission to Intensive Care Units. No limitation regarding gender, race, and ethnicity so that the sample will reflect "typical" Trauma population.

Exclusion Criteria

•All patients admitted under "Doe" Status
•All patients with acute cervical spine injuries or facial fractures that oral care will create further harm to the patient (physician order stating "no oral care to be given" will be in chart)
•All patients with Oral Trauma or Oral Surgery
•All minors (Study will be completed in Adult Critical Care Units)
•Patients with allergy to chlorhexidine
•Patients without Teeth, or with fewer than 6 teeth

Related studies

Pre-clinical Diagnosis Using Integrated Microbial and Host Response Signatures to Improve Outcomes From Ventilator-associated Pneumonia in Critically Ill Children

NCT07026656 · Ventilator Associated Pneumonia ( VAP)

Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens

NCT06554327 · Ventilator Associated Pneumonia

Inspiratory Work of Breathing Before and After Extubation

NCT07017608 · Lung Transplant; Complications, Ventilator-Induced Lung Injury, and more

Antimicrobial Stewardship For Ventilator Associated Pneumonia in Intensive Care

NCT05124977 · Ventilator Associated Pneumonia

Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit

NCT06000761 · Ventilator Associated Pneumonia, Bronchopulmonary Dysplasia, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 6, 2017Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment66

Start dateJul 2010

Last updatedFeb 6, 2017

Condition

Ventilator Associated Pneumonia

Locations shown

St. Joseph's Hospital and Medical Center

Phoenix, Arizona

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 6, 2017Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions