Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica

Exclusion Criteria

• •Cardiac insufficiency; Renal insufficiency; hepatic insufficiency; Total bilirubin higher than 1.5 times of upper limit of normal value; AST /ALT higher than 2.5 times of upper limit of normal value.
• •Combined Pneumonia or other Severe systemic bacteria infection.
• •Severe drug allergic history or anaphylaxis to 2 or more food or medicine.
• •Intracranial hypertension dues to Other brain lesions (eg. Brain cancer)/
• •HIV+, TPPA +， patients diagnosed as HBV or HCV.
• •Tumor Markers +
• •Severe psychotic patients, cognitive dysfunction,Or can not understand or sign the Consent Form.
• •Coagulation disorders.
• •Uncontrolled hypertension after treatment，blood pressure≥180mmHg/110 mmHg.
• •Pregnancy.
• •Enrollment in other trials in the last 3 months.
• •Other criteria the investigator consider improper for inclusion.