Prevention of Photoparoxysmal Abnormalities by Mozart K448

Non-pharmacologic, non-surgical treatments for seizures and epilepsy are of increasing importance, given the potential side effects as well as lack of complete seizure control with such treatments. Based on previous studies demonstrating an anti-convulsant and anti-epileptiform effect achieved in subjects by music exposure, it is proposed that specific musical stimuli may causally result in widely distributed cortical activation in such a fashion as to effectively prevent or terminate epileptiform abnormalities in subjects with photosensitive epilepsy. We will investigate the effect of specific musical stimulation (Mozart K448) to reduce or prevent photoparoxysmal abnormalities in subjects. Primary outcome will be evaluated in 3 groups, assessing alteration/cessation of photic-induced abnormalities during: 1. Treatment: music exposure to Mozart K448, vs. 2. Placebo: music exposure to Beethoven's Für Elise for piano, vs. 3. Control: no music exposure.