1. renal impairment (serum Creatinine above 1.5mg/dL), liver impairment (ALT and AST \> 2x upper limit of normal)

2. any hormonal disorders such as hypothyroidism, hypercortisolemia, hypogonadism, or diabetes mellitus on pharmacotherapy

3. evidence of infections other than HIV in the preceding 3 months

4. subjects with plasma triglyceride concentrations of ≥ 500mg/dL on triglyceride lowering therapy

5. BMI \< 20

6. established heart disease

7. Co-existing viral hepatitis B and C

Role of HIV on Glutathione Synthesis and Oxidative Stress