In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency

Inclusion Criteria

• •Adult male and female subjects, 21-80 years of age
• •Diagnosis of chronic respiratory insufficiency including COPD and interstitial lung disease
• •Requires use of continuous nasal oxygen of at least 2 lpm
• •Reports limitation of activity due to fatigue or breathlessness
• •Fluent in written and spoken English language
• •Ability to be properly fitted with the Breathe nasal mask
• •Ability to tolerate and be appropriately titrated on the Breathe ventilator
• •Ability to communicate self-assessment of dyspnea, comfort, and fatigue
• •Ability and willingness to participate in the study including walking and other activities of daily living
• •Ability to provide written informed consent