Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Kyowa Kirin Co., Ltd.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. 18 years or older
2. Clinical diagnosis of XLH
3. TmP/GFR \< 2.0 mg/dL
4. GFR ≥60 mL/min
5. Corrected Ca \<10.8 mg/dL
6. A willingness to utilize adequate contraception and not become pregnant\[or to have their partner(s) become pregnant\] during the study
You may not be if
1. Have any sign of active infectious disease or have had an infection requiring treatment with antibiotics within 3-weeks of Screening
2. History of known immunodeficiency
3. Pregnant or lactating females subjects or female planning to be become pregnant during the study
4. Receipt of a live (attenuated) vaccine (except for influenza vaccines) within 3-months of Screening, and/or during the study
5. Use of pharmacologic vitamin D metabolite or its analog, phosphate, calcimimetics, and ingestion of aluminum hydroxide antacids within 10-days prior to Screening and/or dosing
6. Use of any supplement containing phosphate, calcium and/or vitamin D within 10-days prior to Screening and/or dosing
7. Condition which could present a concern for either the subject's safety or difficulty with data interpretation
Clareo Health | A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia
