About Pricing FAQs Providers Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDNANCT01335646

Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial

The objective of this study is to determine if surgery is superior to non-operative care for sciatica caused by a lumbar disc herniation. This study will include patients that have had severe sciatica...

Lead sponsor: The London Spine Centre•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

The London Spine Centre

Collaborators

The Physicians' Services Incorporated Foundation
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. 18 - 60 years old
•2. Unilateral, single L5 or S1 radiculopathy (leg pain following dermatomal distribution of L5 or S1)
•* Leg dominant pain over central back pain
•* Positive straight leg raise \<70 degrees
•3. MRI with corresponding L4-5 or L5-S1 posterolateral disc herniation\*
•4. Radicular symptom duration greater than 4 months and less than 12 months. May be recurrent if first episode occurred within 12 months and duration of presenting episode is greater than 4 months.
•5. Agree to possible discectomy

Exclusion Criteria

•1. Radiculopathy secondary to foraminal stenosis
•2. Radiculopathy secondary to intra-foraminal or far lateral disc herniation
•3. Radiculopathy secondary to lumbar central or lateral recess stenosis not caused by a posterolateral disc herniation
•4. Previous lumbar surgery at involved level
•5. Lumbar spondylolisthesis or lateral listhesis at level of disc herniation
•6. Lumbar Scoliosis greater than 10 degrees

Related studies

Efficacy of Combining Mulligan Spinal Mobilization With Leg Movement and Mechanical Lumbar Traction in Lumbar Radiculopathy

NCT07573124 · Lumbar Radiculopathy

R³ Rehab Pathway Versus Usual Care After Lumbar Radicular Surgery

NCT07313566 · Lumbar Radiculopathy, Radicular Low Back Pain

RECRUITINGPhase 4

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

NCT05029726 · Lumbar Spinal Stenosis, Lumbar Disc Herniation, and more

Three-dimensional Lumbar Myofascial Release and Motor Control in Lumbar Radiculopathy

NCT06990113 · Lumbar Radiculopathy

Effects of Adding Balneotherapy to a Physical Therapy Program in Patients With Chronic Lumbar Radiculopathy

NCT06846970 · Lumbar Radiculopathy

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 10, 2020Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment128

Start dateMar 2010

Last updatedMar 10, 2020

Condition

Lumbar Spine Disc Herniation Lumbar Radiculopathy

Locations shown

London Health Science Centre

London, Ontario

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 10, 2020Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions