Curcumin Pharmacokinetics

Exclusion Criteria

• •1. History of any pancreatic or biliary disease (eg. Familial colorectal cancer syndromes, Ulcerative colitis or Crohn's disease)
• •2. History of any acute or chronic illness that requires current medical therapy, including active gastrointestinal conditions, that might interfere with drug absorption
• •3. History of large bowel resection for any reason
• •4. Diagnosed narcotic or alcohol dependence
• •5. Women with childbearing potential who do not agree to practice effective birth control.
• •6. Use of curcumin within the last 14 days
• •7. Allergy to study agent
• •8. Individuals with creatinine, AST or ALT above 1.5 times the upper limit of normal at baseline.
• •9. Personal or inherited bleeding disorders or therapeutic anti-coagulation with warfarin.
• •10. Women who are pregnant or nursing.