Acute ST-elevation myocardial infarction (STEMI)

Culprit coronary lesion with a total thrombotic occlusion or a lesion requiring the use of distal embolization protection or thrombectomy devices

Percutaneous coronary intervention (PCI) within the past 72 hours

Thrombolytic therapy within the past 7 days

Major surgery within the past 3 months

History of cerebral vascular disease or stroke in the past 3 months

Bleeding disorders

Inadequately controlled severe hypertension

Prior coronary artery bypass graft (CABG) surgery

Decompensated heart failure (oedema and/or rale)

Acute infection at screening or active chronic infection within 3 months prior to PCI

Patients known to be HIV positive, patients receiving antiretroviral drugs, or immuno-suppressed patients

Uncontrolled diabetes mellitus (HbA1C \>10%) at baseline

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention