Pregnant or lactating women

Major surgery (including joint surgery) within 8 weeks prior to screening or major surgery planned within 6 months of enrolment

Rheumatic autoimmune disease other than RA

Functional class IV (ACR classification)

Prior history of or current joint disease other than RA

Intraarticular or parenteral corticosteroids within 6 weeks prior to baseline

Previous treatment with RoActemra/Actemra

Known active current or history of recurrent infection

History of or currently active primary or secondary immunodeficiency

Active tuberculosis requiring treatment within the previous 3 years

Positive for HIV

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF