Age

18–65

Sex

ALL

Healthy volunteers

Not accepted

a history of bipolar disorder or anxiety disorder prior to any head injury
a history of head injury in which the cranium was opened either traumatically or surgically
a history of stroke
a history of seizure disorder other than those caused by ethanol withdrawal
evidence of active liver disease
current diagnosis or past history of major psychosis, the alcohol amnesic syndrome, or any type of dementia
current suicidal/homicidal ideations
any medical conditions that would constitute contraindications to treatment with divalproex sodium
currently taking any medications that are known to affect the metabolism of divalproex sodium

Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.