Evaluation of the Impact of Physical Reconditioning Associated With Specific Nutritional Supplementation in Obese Patients Suffering From Metabolic Syndrome

Exclusion Criteria

• •Asthma, chronic respiratory failure, obstructive chronic bronchitis
• •Current or recent Pneumothorax, recent pleural draining or biopsy, current hemoptysis, untreated / in course of treatment active tuberculosis
• •Coronaropathy, myocardiopathy, myocarditis, unstable cardiac failure, ventricular rhythm disorders
• •Severe Anemia
• •Severe inferior members Arteritis
• •Incapacity to walk or cycle
• •Severe renal failure (Creatinine Clearance \<or = 30 mL/min)
• •Severe Sepsis
• •Psychiatric Disorders (Diagnostic and Statistical Manual - Revision 4 (DSM IV) criteria) such as schizophrenia, other psychoses or major depressive non treated syndromes
• •Severe or non treated Eating Disorders implicated in obesity (compulsive access, bulimia)
• •Patients under guardianship or with curators
• •Women in age of procreation without means of effective contraception
• •Pregnant or breast-feeding women
• •Taking medicates such as: proteinate powder (Protifar ®, SP95 ®, Orlistat (Xenical ®, Ally ®), exenatide (Byetta ®), sitagliptin (Januvia ®, Xelevia ®), vildagliptin (Galvus ®), sitagliptin-metformin (Janumet ®), Vildagliptin-metformin (Eucreas ®), tadalafil (Cialis ®) sildenafil (Viagra ®)
• •Drug addiction to opiates in the last six months
• •Alcohol or drug abuse
• •Infection by Human Immunodeficiency Virus (HIV) , viral hepatitis B and viral hepatitis C
• •Active addiction to smoking in more than 8 cigarettes a day
• •Understanding badly spoken or written French
• •Performed, in 2 to 3 days preceding the Dual-energy X-Ray Absorptiometry (DEXA) exam, of a bone scintigraphy or a digestive tract radiological examination with the use of barium type of contrast agent.